5th Edition of International Neurology Conference 2026

Introduction: Meningitis is a significant public health problem in Togo, which records cases of meningococcal outbreaks yearly. In 2014, PCV13 was introduced into the routine EPI. In 2023, the country reported its first pneumococcal meningitis outbreak in the Oti-Sud district. The present study aims to analyze this epidemic.

Methods: This descriptive cross-sectional study is based on epidemiological surveillance data from the Oti-Sud district (population: 125699 inhabitants), analyzed using Epi-Info 7.2.6.0 software. The confidence interval is 95%, with a significance level of less than 0.5%.

Results: The district crossed the epidemic threshold in week 4 of 2023. A total of 149 cases of meningitis were registered, with a cumulative attack rate of 118 per 100,000 inhabitants. The median age was 15 years [11-24 years]. The 5-14 age group was the most represented (64/149 or 42.95%, IC95% = [34.88-51.31]). Children under 5 years were less affected (6%). The M/F sex ratio was 1.07. Only three children under 10 years were vaccinated with PCV13.

Streptococcus pneumoniae was isolated (culture, PCR) in 23 of 128 samples taken (18%); the remaining were negative. The setotyping on 17 cases of Sp have given 11 serotypes 1, 2 serotypes 5 and 4 are no serotype. Four cases of sequelae (headache (1), hypoacusis (1), difficult of concentration (1) and motor deficit (1)) were recorded among confirmed cases (17.39%) and referred for appropriate care. The case-fatality rate was 8.05%.