Background: Intracerebral hemorrhage (ICH) is a clinical subtype of stroke, accounting for approximately 20% of all stroke cases. It carries a high risk of mortality and severe disability. ICH presents with diverse clinical and neuroimaging features. Early diagnosis facilitates timely intervention. Objective: To describe the clinical characteristics and neuroimaging findings in patients with acute intracerebral hemorrhage admitted to S.I.S Can Tho International General Hospital. Methods: A cross-sectional descriptive study was conducted on 140 patients with acute ICH admitted between January 1 and April 30, 2025, at the Can Tho Stroke International Services. Results: males accounted for 62.85%, with an average age of 60.67 ± 8.7 years. The most common symptom was hemiparesis (80.71%), while nausea and vomiting were least common (5.71%). Most patients had a Glasgow Coma Scale (GCS) score of 13–15 (58.58%) and an ICH score of 0–2 (84.28%). The mean blood pressure was 156 ± 24 mmHg. On neuroimaging, the most frequent hemorrhage location was the basal ganglia and thalamus (62.14%). Midline shift was <5 mm in 7.85% of cases, and hematoma volume was <30 ml in 91.43% of patients. Conclusion: Hemiparesis was the most common clinical presentation. Most patients had a GCS >8 and an ICH score <3. Hemorrhages were predominantly located in the basal ganglia and thalamus, with minimal midline shift and small hematoma volumes.